| Sr. Scientist, Pharmacology- location: Woburn, MA
(FullTime) |
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Eyetech is building a state-of-the-art Research and Preclinical Development facility in Lexington, Massachusetts to accommodate its expanding Research & Development efforts. Eyetech is committed to promoting innovative science in a creative and dynamic environment. In addition to retaining staff scientists, Eyetech actively promotes training through MD and PhD fellowship programs
Summary
The successful candidate will lead the development of in vivo and in vitro pharmacology efforts focused on the back of the eye, as well as on diseases where neovascularization plays a significant role. He/She will:
- Identify and implement, externally or internally, appropriate animal models to characterize the PK/PD behavior of our drug candidates
- Develop PK/PD strategies in discovery for selection of new chemical entities for preclinical and clinical development
- Integrate PK/PD from preclinical and clinical studies to facilitate optimal selection of doses in clinical trials
- Establish and improve in vitro / in vivo models relevant to diseases afflicting the back of the eye as well as to other indications.
- Develop new therapeutic regimens for aptamer based therapies
- Design and coordinate internal research and external collaborative studies with academic and contract research labs
- Prepare and review protocols and study reports
- Analyze and present research results at meetings
- Contribute to building our internal capacity in pharmacology, pharmacokinetics, and pharmacodynamics
- (may) Supervise research associate(s).
execute research in support of development projects
Qualifications
- PhD in Pharmacology or Pharmaceutical Science
5+ years post-graduate experience
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Expertise in pharmacology or pharmacokinetics
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Significant and current hands-on in vivo skills to
- validate pre-clinical models
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Strong analytical and problem solving skills
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Excellent organizational, communication, and multitasking skills
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Flexibility and the ability to work in a fast-paced, team-oriented environment
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Exposure to regulatory affairs preferred.
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